Role of Na / H exchanger regulatory factor 1 in forward trafficking of the type
نویسندگان
چکیده
Corey J. Ketchem,* Syed J. Khundmiri,* Adam E. Gaweda, Rebecca Murray, Barbara J. Clark, Edward J. Weinman, and Eleanor D. Lederer Robley Rex Veterans Affairs Medical Center, Louisville, Kentucky; Department of Medicine, University of Louisville, Louisville, Kentucky; Department of Physiology and Biophysics, University of Louisville, Louisville, Kentucky; Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky; and Baltimore Veterans Affairs Medical Center, Baltimore, Maryland; and Department of Medicine, University of Maryland, Baltimore, Maryland
منابع مشابه
Role of Na+/H+ exchanger regulatory factor 1 in forward trafficking of the type IIa Na+-Pi cotransporter.
Na+/H+ exchanger regulatory factor (NHERF1) plays a critical role in the renal transport of phosphate by binding to Na+-Pi cotransporter (NpT2a) in the proximal tubule. While the association between NpT2a and NHERF1 in the apical membrane is known, the role of NHERF1 to regulate the trafficking of NpT2a has not been studied. To address this question, we performed cell fractionation by sucrose g...
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